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1

Interaction Domains of Sos1/Grb2 Are Finely Tuned for Cooperative Control of Embryonic Stem Cell Fate

Findlay, Greg M., Smith, Matthew J., Lanner, Fredrik, Hsiung, Marilyn S., Gish, Gerald D., Petsalaki, Evangelia, Cockburn, Katie, Kaneko, Tomonori, Huang, Haiming, Bagshaw, Richard D., Ketela, Troy, T

Journal:

Year:

2013

Language:

english

File:

PDF, 1.71 MB

english, 2013

2

SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination

Yanling Zhao, Dorothy, Gish, Gerald, Braunschweig, Ulrich, Li, Yue, Ni, Zuyao, Schmitges, Frank W., Zhong, Guoqing, Liu, Ke, Li, Weiguo, Moffat, Jason, Vedadi, Masoud, Min, Jinrong, Pawson, Tony J., B

Journal:

Year:

2015

Language:

english

File:

PDF, 8.95 MB

english, 2015

3

Direct selective pyrophosphorylation of the primary hydroxyl group in (hydroxyethyl)thiamin by modified phosphoric acid-cresol solutions and evaluation of extension of the method to nucleosides

Stephen L. Bearne, Gerald Gish, Khashayar Karimian, Ronald Kluger

Journal:

Bioorganic Chemistry

Year:

1989

Language:

english

File:

PDF, 464 KB

english, 1989

4

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

Holland, Sacha J., Gale, Nicholas W., Gish, Gerald D., Roth, Richard A., Songyang, Zhou, Cantley, Lewis C., Henkemeyer, Mark, Yancopoulos, George D., Pawson, Tony

Journal:

The EMBO Journal

Year:

1997

Language:

english

File:

PDF, 585 KB

english, 1997

5

PTEN regulates cilia through Dishevelled

Shnitsar, Iryna, Bashkurov, Mikhail, Masson, Glenn R., Ogunjimi, Abiodun A., Mosessian, Sherly, Cabeza, Eduardo Aguiar, Hirsch, Calley L., Trcka, Daniel, Gish, Gerald, Jiao, Jing, Wu, Hong, Winklbauer

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 3.88 MB

english, 2015

6

Disentangling the Physical Processes Responsible for the Kinetic Complexity in Interfacial Electron Transfer of Excited Ru(II) Polypyridyl Dyes on TiO 2

Zigler, David F., Morseth, Zachary A., Wang, Li, Ashford, Dennis L, Brennaman, M. Kyle, Grumstrup, Erik M, Brigham, Erinn C., Gish, Melissa K, Dillon, Robert J., Alibabaei, Leila, Meyer, Gerald J., Me

Journal:

Journal of the American Chemical Society

Year:

2016

Language:

english

File:

PDF, 1.83 MB

english, 2016

7

SH2 domain specificity and activity modified by a single residue

Marengere, Luc E. M., Songyang, Zhou, Gish, Gerald D., Schaller, Michael D., Parsons, J. Thomas, Stern, Michael J., Cantley, Lewis C., Pawson, Tony

Journal:

Year:

1994

File:

PDF, 488 KB

1994

8

The Shb scaffold binds the Nck adaptor protein, p120 RasGAP and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2

Wagner, Melany J, Hsiung, Marilyn S, Gish, Gerald D, Bagshaw, Rick D, Doodnauth, Sasha Anita, Soliman, Mohamed A, JÃ¸rgensen, Claus, Tucholska, Monika, Rottapel, Robert

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 2.55 MB

2020

9

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein–protein interactions

Peter van der Geer, Sandra Wiley, Gerald D. Gish, Tony Pawson

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 268 KB

english, 1996

10

Phosphorothioates in molecular biology

Eckstein, Fritz, Gish, Gerald

Journal:

Trends in Biochemical Sciences

Year:

1989

Language:

english

File:

PDF, 489 KB

english, 1989

11

Structural Basis for Specificity Switching of the Src SH2 Domain

Matthew S Kimber, Joseph Nachman, Annie M Cunningham, Gerald D Gish, Tony Pawson, Emil F Pai

Journal:

Year:

2000

Language:

english

File:

PDF, 254 KB

english, 2000

12

Bacterial expression, purification and preliminary kinetic description of the kinase domain of v-fps

Gish, Gerald, McGlone, Maria L., Pawson, Tony, Adams, Joseph A.

Journal:

Protein Engineering Design and Selection

Year:

1995

Language:

english

File:

PDF, 2.24 MB

english, 1995

13

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

Peter van der Geer, Sandra Wiley, Venus Ka-Man Lai, Jean Paul Olivier, Gerald D. Gish, Robert Stephens, David Kaplan, Steven Shoelson, Tony Pawson

Journal:

Current Biology

Year:

1995

Language:

english

File:

PDF, 2.12 MB

english, 1995

14

Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif

Manczyk, Noah, Veggiani, Gianluca, Gish, Gerald D., Yates, Bradley P., Ernst, Andreas, Sidhu, Sachdev S, Sicheri, Frank

Journal:

Protein Science

Year:

2019

Language:

english

File:

PDF, 5.48 MB

english, 2019

15

10.1038/90615

Latour, Sylvain, Gish, Gerald, Helgason, Cheryl D., Humphries, R. Keith, Pawson, Tony, Veillette, André

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 756 KB

english, 2001

16

RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2

Lorenzo, María Jesús, Gish, Gerald D, Houghton, Carol, Stonehouse, Timothy J, Pawson, Tony, Ponder, Bruce AJ, Smith, Darrin P

Journal:

Year:

1997

Language:

english

File:

PDF, 476 KB

english, 1997

17

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

Ingham, Robert J, Gish, Gerald, Pawson, Tony

Journal:

Year:

2004

Language:

english

File:

PDF, 347 KB

english, 2004

18

A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency

Daou, Salima, Talukdar, Manisha, Tang, Jinle, Dong, Beihua, Banerjee, Shuvojit, Li, Yize, Duffy, Nicole M., Ogunjimi, Abiodun A., Gaughan, Christina, Jha, Babal K., Gish, Gerald, Tavernier, Nicolas, M

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 1.53 MB

2020

19

A Rich1/Amot Complex Regulates the Cdc42 GTPase and Apical-Polarity Proteins in Epithelial Cells

Clark D. Wells, James P. Fawcett, Andreas Traweger, Yojiro Yamanaka, Marilyn Goudreault, Kelly Elder, Sarang Kulkarni, Gerald Gish, Cristina Virag, Caesar Lim, Karen Colwill, Andrei Starostine, Pavel

Journal:

Year:

2006

Language:

english

File:

PDF, 1.05 MB

english, 2006

20

Changing incidence of reported viral hepatitis in China from 2004 to 2016: an observational study

Zhang, Mingyuan, Wu, Ruihong, Xu, Hongqin, Uhanova, Julia, Gish, Robert, Wen, Xiaoyu, Jin, Qinglong, Gerald, Minuk Y, Nguyen, M H, Gao, Yanhang, Niu, J

Journal:

Year:

2019

Language:

english

File:

PDF, 1.47 MB

english, 2019

21

Identification of Residues that Control Specific Binding of the Shc Phosphotyrosine-Binding Domain to Phosphotyrosine Sites

Peter Van Der Geer, Sandra Wiley, Gerald D. Gish, Venus Ka-Man Lai, Robert Stephens, Morris F. White, David Kaplan and Tony Pawson

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

22

Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

Sebastian Guettler, Jose LaRose, Evangelia Petsalaki, Gerald Gish, Andy Scotter, Tony Pawson, Robert Rottapel, Frank Sicheri

Journal:

Year:

2012

Language:

english

File:

PDF, 33 KB

english, 2012

23

SH2 and SH3 domains: From structure to function

Tony Pawson, Gerald D. Gish

Journal:

Year:

1992

Language:

english

File:

PDF, 463 KB

english, 1992

24

Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside α-thiotriphosphates

Nakamaye, Kay L., Gish, Gerald, Eckstein, Fritz, Vosberg, Hans-Peter

Journal:

Nucleic Acids Research

Year:

1988

Language:

english

File:

PDF, 1.96 MB

english, 1988

25

Higher-Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function

Zeqiraj, Elton, Tian, Lei, Piggott, Christopher A., Pillon, Monica C., Duffy, Nicole M., Ceccarelli, Derek F., Keszei, Alexander F.A., Lorenzen, Kristina, Kurinov, Igor, Orlicky, Stephen, Gish, Gerald

Journal:

Year:

2015

Language:

english

File:

PDF, 4.77 MB

english, 2015

26

The Shc adaptor protein forms interdependent phosphotyrosine-mediated protein complexes in mast cells stimulated with interleukin 3

Velazquez, Laura, Gish, Gerald D., van der Geer, Peter, Taylor, Lorne, Shulman, Johanna, Pawson, Tony

Journal:

Year:

2000

File:

PDF, 273 KB

2000

27

Thiamin diphosphate catalysis. Mechanistic divergence as a probe of substrate activation of pyruvate decarboxylase

Gish, Gerald., Smyth, Timothy., Kluger, Ronald.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 672 KB

english, 1988

28

Chiral intermediates in thiamin catalysis: Resolution and pyrophosphorylation of hydroxyethylthiamin

Ronald Kluger, Victoria Stergiopoulos, Gerald Gish, Khashayar Karimian

Journal:

Bioorganic Chemistry

Year:

1985

Language:

english

File:

PDF, 505 KB

english, 1985

29

SH2 domains recognize specific phosphopeptide sequences

Songyang Zhou, Steven E. Shoelson, Manas Chaudhuri, Gerald Gish, Tony Pawson, Wayne G. Haser, Fred King, Tom Roberts, Sheldon Ratnofsky, Robert J. Lechleider, Benjamin G. Neel, Raymond B. Birge, J.Edu

Journal:

Year:

1993

Language:

english

File:

PDF, 1.52 MB

english, 1993

30

Role of p120 Ras-GAP in Directed Cell Movement

Sarang V. Kulkarni, Gerald Gish, Peter van der Geer, Mark Henkemeyer and Tony Pawson

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 5.25 MB

english, 2000

31

Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis

Veggiani, Gianluca, Huang, Haiming, Yates, Bradley P., Tong, Jiefei, Kaneko, Tomonori, Joshi, Rakesh, Li, Shawn S-C, Moran, Michael F., Gish, Gerald, Sidhu, Sachdev S.

Journal:

Protein Science

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

32

Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation

Panagis Filippakopoulos, Michael Kofler, Oliver Hantschel, Gerald D. Gish, Florian Grebien, Eidarus Salah, Philipp Neudecker, Lewis E. Kay, Benjamin E. Turk, Giulio Superti-Furga, Tony Pawson, Stefan

Journal:

Year:

2008

Language:

english

File:

PDF, 1.90 MB

english, 2008

33

The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

Wolfgang Vogel, Gerald D Gish, Frauke Alves, Tony Pawson

Journal:

Year:

1997

Language:

english

File:

PDF, 387 KB

english, 1997

34

The K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus Recruits the Endocytic Regulator Intersectin 2 through a Selective SH3 Domain Interaction †

Lim, Caesar S., Seet, Bruce T., Ingham, Robert J., Gish, Gerald, Matskova, Liudmila, Winberg, Gösta, Ernberg, Ingemar, Pawson, Tony

Journal:

Year:

2007

Language:

english

File:

PDF, 733 KB

english, 2007

35

[Methods in Enzymology] Oncogene techniques Volume 254 || [34] Biochemical analysis of SH2 domain-mediated protein interactions

Year:

1995

Language:

english

File:

PDF, 1.85 MB

english, 1995

36

Construction of an SH2 Domain-binding Site with Mixed Specificity

Larose, Louise, Gish, Gerald, Pawson, Tony

Journal:

Journal of Biological Chemistry

Year:

1995

File:

PDF, 5.20 MB

1995

37

Chirality of intermediates in thiamin catalysis: structure of (+)-2-(1-hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium iodide, the absolute stereochemistry of the enantiomers of 2-(1-hydroxyethyl)thiamin, and enzymic reaction of the diphosphates

Kluger, Ronald, Karimian, Khashayar, Gish, Gerald, Pangborn, Walter A., DeTitta, George T.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 394 KB

english, 1987

38

Direct demonstration of an intramolecular SH2—phosphotyrosine interaction in the Crk protein

Rosen, Michael K., Yamazaki, Toshio, Gish, Gerald D., Kay, Cyril M., Pawson, Tony, Kay, Lewis E.

Journal:

Year:

1995

File:

PDF, 305 KB

1995

39

SH2 domains, interaction modules and cellular wiring

Tony Pawson, Gerald D Gish, Piers Nash

Journal:

Trends in Cell Biology

Year:

2001

Language:

english

File:

PDF, 614 KB

english, 2001

40

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

Florian Grebien, Oliver Hantschel, John Wojcik, Ines Kaupe, Boris Kovacic, Arkadiusz M. Wyrzucki, Gerald D. Gish, Sabine Cerny-Reiterer, Akiko Koide, Hartmut Beug, Tony Pawson, Peter Valent, Shohei Ko

Journal:

Year:

2011

Language:

english

File:

PDF, 2.10 MB

english, 2011

41

Twisted amide electrophiles enable cyclic peptide sequencing

Zaretsky, Serge, Rai, Vishal, Gish, Gerald, Forbes, Matthew W., Kofler, Michael, Yu, Joy C. Y., Tan, Joanne, Hickey, Jennifer L., Pawson, Tony, Yudin, Andrei K.

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

42

Kinetics of p56lckand p60srcSrc Homology 2 Domain Binding to Tyrosine-Phosphorylated Peptides Determined by a Competition Assay or Surface Plasmon Resonance

Gillian Payne, Steven E. Shoelson, Gerald D. Gish, Tony Pawson and Christopher T. Walsh

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.04 MB

english, 1993

43

The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1

Yongjian Wu, Monica J.S. Nadler, Laurie A. Brennan, Gerald D. Gish, John F. Timms, Noemi Fusaki, Jenny Jongstra-Bilen, Nobuhiko Tada, Tony Pawson, Joan Wither, Benjamin G. Neel, Nobumichi Hozumi

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 371 KB

english, 1998

44

The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases

Richard Kitching, Michael J. Wong, David Koehler, Angelika M. Burger, Goran Landberg, Gerald Gish, Arun Seth

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2003

Language:

english

File:

PDF, 1.39 MB

english, 2003

45

ChemInform Abstract: Finding the Way to Solar Fuels with Dye-Sensitized Photoelectrosynthesis Cells

Brennaman, M. Kyle, Dillon, Robert J., Alibabaei, Leila, Gish, Melissa K., Dares, Christopher J., Ashford, Dennis L., House, Ralph L., Meyer, Gerald J., Papanikolas, John M., Meyer, Thomas J.

Journal:

Year:

2016

File:

PDF, 16 KB

2016

46

Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

Gruenheid, Samantha, DeVinney, Rebekah, Bladt, Friedhelm, Goosney, Danika, Gelkop, Sigal, Gish, Gerald D., Pawson, Tony, Finlay, B. Brett

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 785 KB

english, 2001

47

Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A

Shun-Cheng Li, Gerald Gish, Daiwen Yang, Alison J. Coffey, Julie D. Forman-Kay, Ingemar Ernberg, Lewis E. Kay, Tony Pawson

Journal:

Current Biology

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

48

Nucleic acids. 11. Synthesis of 5'-esters of 1-.beta.-D-arabinofuranosylcytosine possessing antileukemic and immunosuppressive activity

Gish, Duane T., Kelly, Robert C., Camiener, Gerald W., Wechter, William J.

Journal:

Journal of Medicinal Chemistry

Year:

1971

Language:

english

File:

PDF, 519 KB

english, 1971

49

Transgenic RNA interference in ES cell–derived embryos recapitulates a genetic null phenotype

Kunath, Tilo, Gish, Gerald, Lickert, Heiko, Jones, Nina, Pawson, Tony, Rossant, Janet

Journal:

Nature Biotechnology

Year:

2003

Language:

english

File:

PDF, 481 KB

english, 2003

50

Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

Sebastian Guettler, Jose LaRose, Evangelia Petsalaki, Gerald Gish, Andy Scotter, Tony Pawson, Robert Rottapel, Frank Sicheri

Journal:

Year:

2011

Language:

english

File:

PDF, 2.53 MB

english, 2011

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